Objective To explore the clinical effectiveness of an improved epidural catheter fixation method in labor analgesia and evaluate its impact on anesthesia-related indicators, adverse events rate, epidural catheter placement outcomes, and patient experience. Methods A retrospective analysis was conducted on 1376 parturients who received labor analgesia at a hospital between January 2021 and June 2022. Based on the epidural catheter fixation method, patients were divided into a control group (810 cases, traditional adhesive tape fixation) and an observation group (566 cases, improved epidural catheter fixation). The two groups were compared in terms of anesthesia onset time, analgesia duration, catheter dislodgement rate, adverse events rate, clinical discomfort rate, and catheter placement indicators. Results Compared to the control group, the observation group had a faster anesthesia onset [(6.80±1.00) min vs(7.50±1.20) min, P<0.001] and a longer analgesia duration [(112.30±10.80) min vs (95.60±12.40) min, P<0.001]. The catheter dislodgement rate of the observation group was 0, significantly lower than that in the control group (P=0.044), the first-attempt success rate was higher (98.59% vs 92.59%, P <0.001), while the rates of vascular catheterization and nerve root irritation were significantly reduced (P<0.01). Additionally, the observation group had a lower adverse events rate (2.47% vs 6.17%, P<0.001) and less clinical discomfort rate (1.06% vs 3.46%, P=0.001). Conclusion The improved epidural catheter fixation significantly enhanced the stability of epidural catheter fixation, improved labor analgesia outcomes, reduced adverse events the and clinical discomfort, and demonstrated high clinical practicability and value for widespread implementation.